Special section on clinical trials in io
In this special section, guest edited by Laura Crocetti and Martijn Meijerink, leading experts explore how retrospective data, real world evidence, trial design, economic literacy, meta analysis, and artificial intelligence are shaping a more mature and sustainable scientific foundation of IO. Together, these articles offer practical insights and forward looking perspectives that go well beyond the procedure itself.
Issue: May 2026
Clinical Trials in Interventional Oncology: A Field Growing Up Fast
Martijn R. Meijerink & Laura Crocetti
Survival and Surrogate
Biomarkers in Interventional Oncology Trials: Pitfalls, Challenges, and Future Directions
Ana P. Gonzalez, Adam Swersky & Riad Salem
Retrospective Clinical Studies
in Interventional Oncology: Relevance and Challenges
Johannes Uhlig, Thomas Kroencke & Hyun S. Kim
Real-World Evidence: Better
than Nothing or the Future? A Perspective on Clinical Evidence Generation in Interventional Oncology
Nathalie C. Kaufmann & Philippe L. Pereira
Meta-Analysis: The Holy
Grail?
Danielle J. W. Vos, Hannah H. Schulz & Martijn R. Meijerink
Is Innovation Worth the Price?
Cost-Effectiveness Analysis in Interventional Oncology
Ludovico Cavallaro & Carla Rognoni
The Role of AI in Clinical
Trial Design and Scientific Writing
Niki Katsara Antonakea, Julius Chapiro & Jeff Geschwind
Why is p-Value
Controversial?
Alessandro Vitale, Mohammad Ali Mansournia & Alessandro Rovetta